July 2015

Permissive vaccines and viral virulence

A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses? This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, and are therefore removed by selection. However a vaccine …

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Principles of Virology, Fourth Edition

I am pleased to announce the publication by ASM Press of the fourth edition of our virology textbook, Principles of Virology. Two years in the making, this new edition is fully updated to represent the rapidly changing field of virology. Principles of Virology has been written according to the authors’ philosophy that the best approach to teaching introductory …

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Transgenic pigs resistant to foot-and-mouth disease

Foot-and-mouth disease virus (FMDV) infects cloven-hoofed animals such as cattle, pigs, sheep, goats, and many wild species. The disease caused by this virus is a substantial problem for farmers because infected animals cannot be sold. Transgenic pigs have now been produced which express a short interfering RNA (siRNA) and consequently have reduced susceptibility to infection with FMDV. …

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TWiV 346: A double helical career

Episode #346 of the science show This Week in Virology was recorded at the 34th Annual Meeting of the American Society for Virology, where Vincent, Rich, and Kathy spoke with Joan Steitz, a tireless promoter of women in science and one of the greatest scientists of our generation. You can find TWiV #346 at www.microbe.tv/twiv.

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