Virology lecture #17: Acute infections


Download: .wmv (322 MB) | .mp4 (91 MB)

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  • gsgs

    can you make it just a bit louder ? I have to use max.volume.
    There should be simple software to increase volume – I don't know.

    I'm wondering : why do viruses cause symptoms ?
    Apparantly this is not necessary to replicate and spread.
    And it's a disadvantage because it provokes host behaviour response.
    Is it just a weakness to be removed by further evolution ?

    Can there be many asymptomatic viruses out there not yet detected ?

    Influenza A as a bird-disease causes severe pandemics in humans or poultry.
    Influenza B a a human disease is more constant and usually less virulent.
    Influenza C is even older for humans and only like a cold.

    strategy : make viruses less virulent, release them and let them outcrowd the original strains

    47:20 : VRR could infect all students with measles in one lesson by just talking !

    if measles learns to evade immunity like flu that could be a very
    dangerous/successful virus

  • I'll work on the audio. Why do viruses cause symptoms? Most of the
    time it's the immune response. Early virus detection by the innate
    response leads to production of pro-inflammatory cytokines, which
    cause rubor, dolor, calor, tumor. For those viruses that are
    cytopathic (eg influenza) there is the tissue damage caused by the
    virus; but many early symptoms are the hosts' fault. And yes, there
    are plenty of asymptomatic infections out there – many of us are
    infected with any number of viruses and don't know it. As are many
    animals in the wild.

  • I'll work on the audio. Why do viruses cause symptoms? Most of the
    time it's the immune response. Early virus detection by the innate
    response leads to production of pro-inflammatory cytokines, which
    cause rubor, dolor, calor, tumor. For those viruses that are
    cytopathic (eg influenza) there is the tissue damage caused by the
    virus; but many early symptoms are the hosts' fault. And yes, there
    are plenty of asymptomatic infections out there – many of us are
    infected with any number of viruses and don't know it. As are many
    animals in the wild.