Virology lecture #17: Acute infections

20 April 2010


Download: .wmv (322 MB) | .mp4 (91 MB)

Visit the virology W3310 home page for a complete list of course resources.

  • gsgs

    can you make it just a bit louder ? I have to use max.volume.
    There should be simple software to increase volume – I don't know.

    I'm wondering : why do viruses cause symptoms ?
    Apparantly this is not necessary to replicate and spread.
    And it's a disadvantage because it provokes host behaviour response.
    Is it just a weakness to be removed by further evolution ?

    Can there be many asymptomatic viruses out there not yet detected ?

    Influenza A as a bird-disease causes severe pandemics in humans or poultry.
    Influenza B a a human disease is more constant and usually less virulent.
    Influenza C is even older for humans and only like a cold.

    strategy : make viruses less virulent, release them and let them outcrowd the original strains

    47:20 : VRR could infect all students with measles in one lesson by just talking !

    if measles learns to evade immunity like flu that could be a very
    dangerous/successful virus

  • http://www.virology.ws profvrr

    I'll work on the audio. Why do viruses cause symptoms? Most of the
    time it's the immune response. Early virus detection by the innate
    response leads to production of pro-inflammatory cytokines, which
    cause rubor, dolor, calor, tumor. For those viruses that are
    cytopathic (eg influenza) there is the tissue damage caused by the
    virus; but many early symptoms are the hosts' fault. And yes, there
    are plenty of asymptomatic infections out there – many of us are
    infected with any number of viruses and don't know it. As are many
    animals in the wild.

  • http://www.virology.ws profvrr

    I'll work on the audio. Why do viruses cause symptoms? Most of the
    time it's the immune response. Early virus detection by the innate
    response leads to production of pro-inflammatory cytokines, which
    cause rubor, dolor, calor, tumor. For those viruses that are
    cytopathic (eg influenza) there is the tissue damage caused by the
    virus; but many early symptoms are the hosts' fault. And yes, there
    are plenty of asymptomatic infections out there – many of us are
    infected with any number of viruses and don't know it. As are many
    animals in the wild.