Comments on: Virology lecture #4: Structure of viruses http://www.virology.ws/2010/02/02/virology-lecture-4-structure-of-viruses/ About viruses and viral disease Sat, 11 Feb 2012 17:38:00 +0000 hourly 1 http://wordpress.org/?v=3.3.1 By: profvrr http://www.virology.ws/2010/02/02/virology-lecture-4-structure-of-viruses/comment-page-1/#comment-22488 profvrr Fri, 02 Jul 2010 03:08:27 +0000 http://www.virology.ws/?p=2752#comment-22488 The viral envelope is derived from the mammalian host cell and is<br>therefore very similar in composition, with the exception that most<br>cellular membrane proteins are excluded from the viral envelope. Both<br>bacterial and mammalian membranes are typical phospholipid bilayers,<br>although the proteins embedded in them are different. For a novel<br>antiviral compound that targets the viral envelope, see<br><a href="http://www.virology.ws/2010/02/18/an-antiviral-for-enveloped-viruses/" rel="nofollow">http://www.virology.ws/2010/02/18/an-antiviral-...</a> The viral envelope is derived from the mammalian host cell and is
therefore very similar in composition, with the exception that most
cellular membrane proteins are excluded from the viral envelope. Both
bacterial and mammalian membranes are typical phospholipid bilayers,
although the proteins embedded in them are different. For a novel
antiviral compound that targets the viral envelope, see
http://www.virology.ws/2010/02/18/an-antiviral-…

]]> By: Pritesh http://www.virology.ws/2010/02/02/virology-lecture-4-structure-of-viruses/comment-page-1/#comment-22429 Pritesh Tue, 29 Jun 2010 07:47:42 +0000 http://www.virology.ws/?p=2752#comment-22429 Dr. Racaniello,<br><br>Wonderful lecture !<br><br>Few questions, <br>So viral envelope is composed of glycoproteins, some of which are essential in attachment and entry. What else is envelope made of ? Lipid bilayer ..? and how similar is this lipid bilayer to mammalian cells or bacterial cell bilayer ? <br>Also I read somewhere or may be in one of the TWiV's that envelope viruses cannot survive without the envelope. I see many antiviral compounds targeting the viral glycoprotein or corresponding cell receptor. But is there some significant work done of disrupting the viral envelope ? <br><br>Thank you,<br>Pritesh Dr. Racaniello,

Wonderful lecture !

Few questions,
So viral envelope is composed of glycoproteins, some of which are essential in attachment and entry. What else is envelope made of ? Lipid bilayer ..? and how similar is this lipid bilayer to mammalian cells or bacterial cell bilayer ?
Also I read somewhere or may be in one of the TWiV's that envelope viruses cannot survive without the envelope. I see many antiviral compounds targeting the viral glycoprotein or corresponding cell receptor. But is there some significant work done of disrupting the viral envelope ?

Thank you,
Pritesh

]]> By: gsgs http://www.virology.ws/2010/02/02/virology-lecture-4-structure-of-viruses/comment-page-1/#comment-21655 gsgs Wed, 03 Feb 2010 17:25:29 +0000 http://www.virology.ws/?p=2752#comment-21655 viruses are not exactly like houses, they are like ...(make a poll)<br>why angstroem, when we have nanometers<br>why is there no structure inside the virus to stabilize the shell ? (walls,rooms in houses)<br>why only icosahedrons, are dodecahedrons,... impossible in principle or were they once<br>eliminated in the great intervirotic war<br>how are these t=1,2,...facet-icosahedrons called in math ? I remember webpages where you can<br>rotate all these shapes with the mouse , or virus-models from plastic or videos rotating them<br>do viruses attach to each other to form polyicosahedra<br>need an organized list of all known viruses (how many in total) with their properties and pictures<br>when you say:"see here" , there is no pointer in the video<br>hyperlinks to click while you talk would be nice<br><a href="http://viperdb.scripps.edu" rel="nofollow">http://viperdb.scripps.edu</a> viruses are not exactly like houses, they are like …(make a poll)
why angstroem, when we have nanometers
why is there no structure inside the virus to stabilize the shell ? (walls,rooms in houses)
why only icosahedrons, are dodecahedrons,… impossible in principle or were they once
eliminated in the great intervirotic war
how are these t=1,2,…facet-icosahedrons called in math ? I remember webpages where you can
rotate all these shapes with the mouse , or virus-models from plastic or videos rotating them
do viruses attach to each other to form polyicosahedra
need an organized list of all known viruses (how many in total) with their properties and pictures
when you say:”see here” , there is no pointer in the video
hyperlinks to click while you talk would be nice
http://viperdb.scripps.edu

]]> By: gsgs http://www.virology.ws/2010/02/02/virology-lecture-4-structure-of-viruses/comment-page-1/#comment-20184 gsgs Wed, 03 Feb 2010 09:25:29 +0000 http://www.virology.ws/?p=2752#comment-20184 viruses are not exactly like houses, they are like ...(make a poll)<br>why angstroem, when we have nanometers<br>why is there no structure inside the virus to stabilize the shell ? (walls,rooms in houses)<br>why only icosahedrons, are dodecahedrons,... impossible in principle or were they once<br>eliminated in the great intervirotic war<br>how are these t=1,2,...facet-icosahedrons called in math ? I remember webpages where you can<br>rotate all these shapes with the mouse , or virus-models from plastic or videos rotating them<br>do viruses attach to each other to form polyicosahedra<br>need an organized list of all known viruses (how many in total) with their properties and pictures<br>when you say:"see here" , there is no pointer in the video<br>hyperlinks to click while you talk would be nice<br><a href="http://viperdb.scripps.edu" rel="nofollow">http://viperdb.scripps.edu</a> viruses are not exactly like houses, they are like …(make a poll)
why angstroem, when we have nanometers
why is there no structure inside the virus to stabilize the shell ? (walls,rooms in houses)
why only icosahedrons, are dodecahedrons,… impossible in principle or were they once
eliminated in the great intervirotic war
how are these t=1,2,…facet-icosahedrons called in math ? I remember webpages where you can
rotate all these shapes with the mouse , or virus-models from plastic or videos rotating them
do viruses attach to each other to form polyicosahedra
need an organized list of all known viruses (how many in total) with their properties and pictures
when you say:”see here” , there is no pointer in the video
hyperlinks to click while you talk would be nice
http://viperdb.scripps.edu

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