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viruses are not exactly like houses, they are like …(make a poll)why angstroem, when we have nanometerswhy is there no structure inside the virus to stabilize the shell ? (walls,rooms in houses)why only icosahedrons, are dodecahedrons,… impossible in principle or were they onceeliminated in the great intervirotic warhow are these t=1,2,…facet-icosahedrons called in math ? I remember webpages where you canrotate all these shapes with the mouse , or virus-models from plastic or videos rotating themdo viruses attach to each other to form polyicosahedraneed an organized list of all known viruses (how many in total) with their properties and pictureswhen you say:”see here” , there is no pointer in the videohyperlinks to click while you talk would be nicehttp://viperdb.scripps.edu
Wonderful lecture !
Few questions, So viral envelope is composed of glycoproteins, some of which are essential in attachment and entry. What else is envelope made of ? Lipid bilayer ..? and how similar is this lipid bilayer to mammalian cells or bacterial cell bilayer ? Also I read somewhere or may be in one of the TWiV's that envelope viruses cannot survive without the envelope. I see many antiviral compounds targeting the viral glycoprotein or corresponding cell receptor. But is there some significant work done of disrupting the viral envelope ?
The viral envelope is derived from the mammalian host cell and istherefore very similar in composition, with the exception that mostcellular membrane proteins are excluded from the viral envelope. Bothbacterial and mammalian membranes are typical phospholipid bilayers,although the proteins embedded in them are different. For a novelantiviral compound that targets the viral envelope, seehttp://www.virology.ws/2010/02/18/an-antiviral-…
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by Vincent Racaniello
Earth’s virology course
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