Comments on: TWiV 47: Vertical vaccine farm

By: BrianHanley

BrianHanley — Tue, 24 Nov 2009 04:55:42 +0000

Plant derived virus particles are definitely practical. There are a number of plant viruses that are excellent for that purpose. Tobacco is a nice plant to use because of TMV (tobacco mosaic virus), but there are others. There are good methods for purification such as Watanabe 1952 or Gooding 1967 http://www.ncbi.nlm.nih.gov/pubmed/6075009

Early vaccine studies have been done. (Ex: http://www.nature.com/nbt/journal/v13/n1/abs/nb... )

Try talking to Bryce Falk at UCD. He's very knowledgable about TMV and other viruses for protein expression. bwfalk@ucdavis.edu

By: BrianHanley

BrianHanley — Mon, 23 Nov 2009 20:55:42 +0000

By: Do women need the same amount of influenza vaccine as men?

Do women need the same amount of influenza vaccine as men? — Mon, 16 Nov 2009 14:20:53 +0000

[...] My conclusion is that it would not be possible to determine conclusively that women could receive half the amount of inactivated influenza virus vaccine as men. I would rather spend money on developing new ways to produce as much influenza vaccine as needed as quickly as possible – such as by making virus-like particles in plants. [...]

By: TWiV 47: Vertical vaccine farm virology

TWiV 47: Vertical vaccine farm virology — Sat, 12 Sep 2009 05:48:14 +0000

[...] Originally posted here: TWiV 47: Vertical vaccine farm [...]