TWiV 46: Virus entry into cells

23 August 2009

twiv-200Hosts: Vincent Racaniello and Dick Despommier

In episode #46 of the podcast “This Week in Virology”, Vincent and Dick continue virology 101 with a discussion of virus entry into cells, then answer reader email on colony collapse disorder and viruses that confer a benefit to their host.

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Click the arrow above to play, or right-click to download TWiV #46 (35 MB .mp3, 50 minutes)

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Links for this episode:
Illustrations of virus entry into cells
Nice reference for biological items (thanks Jim!)
Colony collapse disorder: PBS program,  descriptive studymetagenomic study, genetic analysis (thanks Swiss compass!)
Potato virus Y and Alzheimer’s disease (thanks Jennifer!)
virus in a fungus in a plant (thanks Jennifer!)

Weekly Science Picks
Vincent PLoS Pearls
Dick West Nile virus website at CDC

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast

  • mojo1372

    I am a lay person but I was interested in a story I heard about a researcher or doctor who was studing a mutation of cell 25. he was living in manhattan studing men who had put themselfs at very high risk of catching aids from many partners who died of the sickness yet some never got sick and some took many years before they showed symptoms of the sickness. once conclusions was they all were from european back ground . he got into there family histories going way back he found that their relatives going back to some of the black plague outbreak never got sick even though people all around them died in some cases the majority of a village where an ancestor lived never got sick because they all were related down the line .so he started studing the cells of the men here and cells from people on the other side who decendant survied the plague the one thing he found in common was they all had a mution in cell 25 . when exposed to the hiv virus would not allow the virus to enter the cell because of this mutation . he found the men who both parents had the mutation did not get sick at all and the men who had one parent with the mutation may have taken as many as 10 years from exposure to hiv get ill . has anyone heard anything on this study ?

  • mojo1372

    I am a lay person but I was interested in a story I heard about a researcher or doctor who was studing a mutation of cell 25. he was living in manhattan studing men who had put themselfs at very high risk of catching aids from many partners who died of the sickness yet some never got sick and some took many years before they showed symptoms of the sickness. once conclusions was they all were from european back ground . he got into there family histories going way back he found that their relatives going back to some of the black plague outbreak never got sick even though people all around them died in some cases the majority of a village where an ancestor lived never got sick because they all were related down the line .so he started studing the cells of the men here and cells from people on the other side who decendant survied the plague the one thing he found in common was they all had a mution in cell 25 . when exposed to the hiv virus would not allow the virus to enter the cell because of this mutation . he found the men who both parents had the mutation did not get sick at all and the men who had one parent with the mutation may have taken as many as 10 years from exposure to hiv get ill . has anyone heard anything on this study ?