Comments on: Coxsackie NY and the virus named after it http://www.virology.ws/2009/08/10/coxsackie-ny-and-the-virus-named-after-it/ About viruses and viral disease Sat, 11 Feb 2012 17:38:00 +0000 hourly 1 http://wordpress.org/?v=3.3.1 By: Tony Mach http://www.virology.ws/2009/08/10/coxsackie-ny-and-the-virus-named-after-it/comment-page-1/#comment-27851 Tony Mach Tue, 14 Jun 2011 17:37:00 +0000 http://www.virology.ws/?p=1891#comment-27851 Better to post it here than on the XMRV posts... From what I have read sofar, I think Enteroviruses are behind ME/CFS.First of all, there is the most recent work by Dr. John Chia. He finds VP1 enterovirus protein in about 80% of gut biopsies of people with ME/CFS he tested. Furthermore the viruses he find show about 80% homology to Coxsackie B.http://chronicfatigue.stanford.edu/infections/entero-experts.htmlThe work of John Chia is based on the earlier work of British scientists, mainly James Mowbray (if I'm not mistaken) who was the first to find VP1 in gut and muscle biopsies of ME/CFS patients. But for me the key (and the best clinical description of the earlier outbreaks of ME/CFS I could find) is "The saga of Royal Free disease" by A. Melvin Ramsay: He describes how in villages in Icland in 1948 that suffered an ME/CFS outbreak were sparred from a following Polio outbreak that hit other villages. And he describes how an Polio outbreak in Adelaide ceased abruptly to be replaced by an ME/CFS outbreak. Furthermore, if you haven't read it, I can recommend the book Osler's Web to get a feeling why ME/CFS is such a minefield - and a nightmare for those suffering from this disease. Better to post it here than on the XMRV posts…

From what I have read sofar, I think Enteroviruses are behind ME/CFS.First of all, there is the most recent work by Dr. John Chia. He finds VP1 enterovirus protein in about 80% of gut biopsies of people with ME/CFS he tested. Furthermore the viruses he find show about 80% homology to Coxsackie B.http://chronicfatigue.stanford.edu/infections/entero-experts.htmlThe work of John Chia is based on the earlier work of British scientists, mainly James Mowbray (if I’m not mistaken) who was the first to find VP1 in gut and muscle biopsies of ME/CFS patients.

But for me the key (and the best clinical description of the earlier outbreaks of ME/CFS I could find) is “The saga of Royal Free disease” by A. Melvin Ramsay: He describes how in villages in Icland in 1948 that suffered an ME/CFS outbreak were sparred from a following Polio outbreak that hit other villages. And he describes how an Polio outbreak in Adelaide ceased abruptly to be replaced by an ME/CFS outbreak.

Furthermore, if you haven’t read it, I can recommend the book Osler’s Web to get a feeling why ME/CFS is such a minefield – and a nightmare for those suffering from this disease.

]]> By: Anonymous http://www.virology.ws/2009/08/10/coxsackie-ny-and-the-virus-named-after-it/comment-page-1/#comment-26369 Anonymous Fri, 29 Apr 2011 16:56:00 +0000 http://www.virology.ws/?p=1891#comment-26369 This one is very nice and excellent information and post of Exit.I like this Exit logo and information board design.I love this nice post. <a href="http://www.globritesystem.com" rel="nofollow">exit signs</a> This one is very nice and excellent information and post of Exit.I like this Exit logo and information board design.I love this nice post.

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]]> By: Nasim Marie Jafry http://www.virology.ws/2009/08/10/coxsackie-ny-and-the-virus-named-after-it/comment-page-1/#comment-25374 Nasim Marie Jafry Wed, 09 Feb 2011 21:04:00 +0000 http://www.virology.ws/?p=1891#comment-25374 Interesting, I didn't realise the name was of native American origin. I became ill with ME/CFS after an outbreak of Coxsackie B4 in west of Scotland in 1983. Interesting, I didn’t realise the name was of native American origin. I became ill with ME/CFS after an outbreak of Coxsackie B4 in west of Scotland in 1983.

]]> By: profvrr http://www.virology.ws/2009/08/10/coxsackie-ny-and-the-virus-named-after-it/comment-page-1/#comment-21749 profvrr Mon, 10 Aug 2009 19:24:31 +0000 http://www.virology.ws/?p=1891#comment-21749 The first Coxsackievirus was identified in 1947 in paralyzed children.<br>Subsequently about 29 more related viruses were identified that cause<br>a variety of clinical syndromes, including blisters and fever. Because<br>all 30 viruses were highly related, they were called Coxsackieviruses,<br>even though they were not isolated from that town. The first Coxsackievirus was identified in 1947 in paralyzed children.
Subsequently about 29 more related viruses were identified that cause
a variety of clinical syndromes, including blisters and fever. Because
all 30 viruses were highly related, they were called Coxsackieviruses,
even though they were not isolated from that town.

]]> By: trinetsouderos http://www.virology.ws/2009/08/10/coxsackie-ny-and-the-virus-named-after-it/comment-page-1/#comment-21748 trinetsouderos Mon, 10 Aug 2009 19:15:21 +0000 http://www.virology.ws/?p=1891#comment-21748 Vincent, How did one specific virus - the typical childhood one that that gave my son blisters in his mouth and a high fever for three days - end up being known as Coxsackievirus, while the rest are not? T Vincent, How did one specific virus – the typical childhood one that that gave my son blisters in his mouth and a high fever for three days – end up being known as Coxsackievirus, while the rest are not? T

]]> By: profvrr http://www.virology.ws/2009/08/10/coxsackie-ny-and-the-virus-named-after-it/comment-page-1/#comment-16135 profvrr Mon, 10 Aug 2009 12:24:31 +0000 http://www.virology.ws/?p=1891#comment-16135 The first Coxsackievirus was identified in 1947 in paralyzed children.<br>Subsequently about 29 more related viruses were identified that cause<br>a variety of clinical syndromes, including blisters and fever. Because<br>all 30 viruses were highly related, they were called Coxsackieviruses,<br>even though they were not isolated from that town. The first Coxsackievirus was identified in 1947 in paralyzed children.
Subsequently about 29 more related viruses were identified that cause
a variety of clinical syndromes, including blisters and fever. Because
all 30 viruses were highly related, they were called Coxsackieviruses,
even though they were not isolated from that town.

]]> By: trinetsouderos http://www.virology.ws/2009/08/10/coxsackie-ny-and-the-virus-named-after-it/comment-page-1/#comment-16134 trinetsouderos Mon, 10 Aug 2009 12:15:21 +0000 http://www.virology.ws/?p=1891#comment-16134 Vincent, How did one specific virus - the typical childhood one that that gave my son blisters in his mouth and a high fever for three days - end up being known as Coxsackievirus, while the rest are not? T Vincent, How did one specific virus – the typical childhood one that that gave my son blisters in his mouth and a high fever for three days – end up being known as Coxsackievirus, while the rest are not? T

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