Comments on: Reassortment of the influenza virus genome

By: webmastersurajit

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By: Joe

Joe — Wed, 25 Aug 2010 01:54:27 +0000

The reason the CDC can use a binomial classification is because the current antiviral drugs act in a specific manner such that there are specific base pair positions that can be looked at and if there is a mutation that causes an amino acid substitution at that postition, the antiviral will either work or it won't. So you can't get any answer other than yes or no.

By: What if influenza virus did not reassort?

What if influenza virus did not reassort? — Tue, 15 Sep 2009 12:01:31 +0000

[...] influenza virus be the same pathogen if it could not undergo reassortment of its segmented RNA genome? This is the question being asked in the wake of the development of a [...]

By: Pandemic H1N1 influenza virus outcompetes seasonal strains in ferrets

Pandemic H1N1 influenza virus outcompetes seasonal strains in ferrets — Thu, 10 Sep 2009 12:02:36 +0000

[...] cells with two viruses can lead to the production of genetically distinct viruses by the process of reassortment of viral RNAs. Experiments have been done in ferrets to determine how the 2009 pandemic H1N1 strain [...]

By: Twitter Trackbacks for Reassortment of the influenza virus genome [virology.ws] on Topsy.com

Tue, 25 Aug 2009 13:30:44 +0000

[...] Reassortment of the influenza virus genome http://www.virology.ws/2009/06/29/reassortment-of-the-influenza-virus-genome – view page – cached #virology blog » Reassortment of the influenza virus genome Comments Feed virology blog RSS Feed — From the page [...]

By: p_k_suresh

p_k_suresh — Sun, 23 Aug 2009 14:34:01 +0000

My question is two fold:

1. What is the known rate of evolution that has led to the current outbreak ? This question should be seen in the context of avian flu (birds were culled in India during that outbreak)?

2. In the context of Darwinian principles, can this type of repeated pandemics lead to the extinction of the human species ? ("are the microbes the real rulers of this world"). This question should seen in the context of the fitness of the host being important for the viral multiplication. (What percentage of the microbes are parasites and if the parasites lose out due to selective pressures, in the future, would it affect the ecological balance ?)

3. What about the prophylactic measures from the environmental point of view ?

Thanks,

P.K.Suresh

By: p_k_suresh

p_k_suresh — Sun, 23 Aug 2009 07:34:01 +0000

By: Insider

Insider — Thu, 09 Jul 2009 15:30:38 +0000

A/H1N1 is a Biological Binary Weapon, we are under BW attack, standard medical procedures
are not the right aproach to this virus, you have to learn the military way of doing it.

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By: bartelsontour

bartelsontour — Thu, 09 Jul 2009 14:42:52 +0000

world Wave graph on : http://bartelsontour.webs.com

By: Everything you wanted to know about reassortment but were afraid to ask | Swine Flu Daily Update

Wed, 01 Jul 2009 22:45:15 +0000

[...] Vincent Racaniello at virology blog has posted the best explanation I've ever read on Reassortment of the influenza virus genome. Now I think I understand how the present strain of H1N1 emerged from swine, human, and avian flu [...]

By: profvrr

profvrr — Wed, 01 Jul 2009 10:59:35 +0000

You are right, thank you for the correction. The post has been updated.

By: David

David — Tue, 30 Jun 2009 11:51:59 +0000

And in other news...Denmark is reporting the first case of resistance to Tamiflu: http://news.yahoo.com/s/nm/20090629/ts_nm/us_de...

Vincent, do you have a piece on antiviral resistance? I need to learn more on this topic. I noticed that CDC reports on isolates that are resistant to the various antiviral drugs but shouldn’t there be a continuum considered - not just a binomial classification (yes/no)? For example – how ‘resistant’ is the viral to the drug considered?

By: Raj

Raj — Mon, 29 Jun 2009 14:34:44 +0000

“Reassortment can only occur between influenza viruses of the same subtype”

I think reassortment can occur between influenza viruses of same type but different subtypes
e.g. between Influenza type A subtype H1N1 and Influenza type A subtype H2N2