Comments on: Structure of influenza virus

By: Jason

Jason — Wed, 08 Feb 2012 11:15:00 +0000

To all those haters, if you don’t like it, you don’t need to start whining. This article is helpful and if you didn’t like it, go sook in a corner.

By: Eager learner

Eager learner — Mon, 09 Jan 2012 21:47:00 +0000

All those who are posting complaints about either the grammatical quality of this text or the scientific detail, go somewhere else if it is too advanced for you. This is written by a professor who knows lots about this subject. You are wasting his time. Thank you Vincent Racaniello this article is very helpful.

By: Ggllt

Ggllt — Mon, 09 Jan 2012 02:58:00 +0000

tits

By: RachelDawn

RachelDawn — Fri, 06 Jan 2012 00:52:00 +0000

Really helpful, it’s so hard to find an explanation of this at the right level for what I need!

By: Bi 11 girl

Bi 11 girl — Thu, 03 Nov 2011 21:42:00 +0000

there should be better deffentions for some of the more scientific words here, explaining how they work in the body

By: Feastingwithbears

Feastingwithbears — Tue, 27 Sep 2011 06:37:00 +0000

You are rather uninformative and not helpful. The rest of you giving scientific answers and comments are about as helpful as a toddler in the trenches, that is to say I would use you as a human shield (I do not condone family violence however, this is merely an example of my feelings towards you). The majority of people viewing this article want a basic run through on the life processes of the virus, not a lecture on the structure of viruses in our world. I am doing a school project and was thoroughly disappointed with the amount of confusing (to some) scientific comments, the only productive comment was “poopy” sums up this article pretty well I think.

Kind Regards, your life advisor.

By: TAJMA

TAJMA — Fri, 23 Sep 2011 10:36:00 +0000

can you breakdown the biology of influenza? please

By: Gasp

Gasp — Wed, 31 Aug 2011 01:35:00 +0000

improve your sentences’ and grammer, and get your sentences stright and to the point, and the structure of the cell is wrong, firstly the reason scientists couldn’ t find an cure so fast was because once the cell came into contact with anti-bodies the cell use them to it’s adventage -gasp

By: Microbioogy student

Microbioogy student — Sat, 09 Jul 2011 07:15:00 +0000

If you read it, he says that the HA NA determine the subtype

By: Dalila Lepirica

Dalila Lepirica — Tue, 14 Jun 2011 14:39:00 +0000

Very good. =0)

By: Hyun

Hyun — Fri, 06 May 2011 01:55:00 +0000

Thank you for useful information!
I think you should correct ‘diagram: B1, PB2 …’–> to ‘diagram: PB1, PB2′ in the following sentence .
“Each RNA segment, as they are called, consists of RNA joined with several proteins shown in the diagram: B1, PB2, PA, NP”

By: John_johnk

John_johnk — Mon, 02 May 2011 04:06:00 +0000

You need gramar lessons.

By: profvrr

profvrr — Fri, 18 Feb 2011 16:20:00 +0000

See http://www.virology.ws/2010/02/11/protection-against-2009-influenza-h1n1-by-immunization-with-1918-like-and-classical-swine-viruses/
and the paper discussed in the post for the antigenic sites.

By: Sujatha

Sujatha — Fri, 18 Feb 2011 09:58:00 +0000

WHAT ARE THE ANTIGENIC SITES PRESENT IN H1N1?

By: profvrr

profvrr — Wed, 02 Feb 2011 14:31:00 +0000

Influenza types were originally (years ago) defined by
cross-reactivity, using antisera, against the core proteins, M1 and
NP. By sequence comparison of HA and NA it would be possible today to
determine whether an influenza virus is type A or B or C. I’ve made a
few corrections to the post to reflect this information.

By: Daniel Condurachi

Daniel Condurachi — Mon, 31 Jan 2011 14:14:00 +0000

you say this
“because they consist of protein linked to sugars – known as HA (hemagglutinin) and NA (neuraminidase). These are the proteins that determine the type of influenza virus (A, B, or C) and”
but HA and NA do not determine the type of influenza virus but only the subtype. NP and M determine the type of influenza virus A, B or C

By: profvrr

profvrr — Thu, 20 Jan 2011 18:39:00 +0000

NEP, or nuclear export protein, is involved in the export of the viral
RNA-protein complex from the nucleus, where the viral RNA is
replicated, to the cytoplasm.

By: Joeya40

Joeya40 — Wed, 19 Jan 2011 22:24:00 +0000

I’m pleased with your explanation. But what is NEP function?

By: Hamish

Hamish — Thu, 06 Jan 2011 12:34:00 +0000

i bought a blood zapper. and read dr becks work for nasa. take vitaminc tablets 1000mg before using a blood zapper. electroporation occurs magnifying the vit c to like 60,ooomg like some armies combi pens. never fear a virus again.

By: Rajan

Rajan — Tue, 04 Jan 2011 03:48:00 +0000

satisfied…

By: Carlos Enriquez

Carlos Enriquez — Mon, 06 Dec 2010 19:06:00 +0000

Influenza virus types are determined by the nucleoprotein rather than the H or N.

Bull World Health Organ. 1971; 45(1): 119–124.

By: Bloop

Bloop — Wed, 01 Dec 2010 05:50:00 +0000

Thank you!!!!!!

By: Hypergurl_321

Hypergurl_321 — Mon, 08 Nov 2010 23:33:00 +0000

how many segments of genetic material do they have?

By: naincy chandan

naincy chandan — Thu, 26 Aug 2010 09:56:11 +0000

sir,is it possible that only 1 virus causes infection??can you plz justify?

By: Remove Spyware

Remove Spyware — Sat, 07 Aug 2010 21:18:38 +0000

Thanks for your explantion about influenza virus.

By: Nama Swaroopa

Nama Swaroopa — Tue, 13 Jul 2010 16:16:08 +0000

it is very much woth enough do continue

By: Adam

Adam — Wed, 26 May 2010 04:08:38 +0000

Virus's arent alive so the difference between “live” and “dead” virus's is a poor question. the destinction between functioning virus's and lysed or defective/inoperative virus's is that they will not produce proteins or if they have been lysed than they will loose there membrane and their contence will be dispersed around the surrounding tissue

By: Yi-Ting Tsai

Yi-Ting Tsai — Wed, 31 Mar 2010 06:52:38 +0000

Obviously, not all viral proteins are included in the virons. I have a question, how do scientists determinate the virus structure? which proteins are included in the virons?
There are two common categories: structure proteins and neucleoproteins. Like poliovirus protein 2B, a short peptide, can scientist certainly exclude that in the virons?

By: Yi-Ting Tsai

Yi-Ting Tsai — Tue, 30 Mar 2010 23:52:38 +0000

By: Subhash Godbole

Subhash Godbole — Tue, 30 Mar 2010 04:13:58 +0000

I am new in the field of Virology. I have one basic question. When we see the structure of a virus, e.g. H1N1 virus, then we find that it is quite simple. Then at structural level, what is the difference between a live virus and a dead virus ?

By: abimbola

abimbola — Thu, 04 Mar 2010 09:29:57 +0000

very useful, would like to see more updates on this.

By: ginabush

ginabush — Fri, 05 Feb 2010 14:54:13 +0000

thats racist

By: chandra_cse

chandra_cse — Fri, 05 Feb 2010 10:03:26 +0000

Hello Respected Professor VRR,
I am chandra sekhar with computer science background,Recently i started my research in bioinformatics, I am very much interested to work with influenza related data,
Could you please suggest me any research problem to work with influenza data .

Thanks in advance

By: Sally Soh

Sally Soh — Wed, 03 Feb 2010 04:06:53 +0000

Hi! I would like to understand how mutation in the HA such as E391K in the trimerization interface may affect the effectiveness of the H1N1 vaccine.

By: profvrr

profvrr — Tue, 19 Jan 2010 19:06:32 +0000

Viruses are not cellular; hence they are not classified as prokaryotic
or eukaryotic.

By: 735019

735019 — Sat, 16 Jan 2010 15:46:39 +0000

this is very good thanks…. i just have one question is the H1N1 virus a prokaryote, eukaryote, or just non-cellular?

By: Tasneem fatima

Tasneem fatima — Sat, 19 Dec 2009 09:54:19 +0000

hey Thank u so much…….its really v v useful…..being micro and biotech student it is highly informativ for me.thnx alot……m lookng frward for more infrmation……

By: profvrr

profvrr — Fri, 18 Dec 2009 12:02:40 +0000

Without HA the virions cannot attach to cell receptors and of course
the virions will not combine with anti-HA antibodies. NA is not
required to infect a cell, but without it, newly synthesized virus
particles cannot be released from the infected cell.

By: yatish kumar

yatish kumar — Fri, 18 Dec 2009 05:01:19 +0000

actually i just wana know that if we will distroy or disturbe the structure or if we remove the spikes (NA/ HA), than can the spreading of this viruse/ joining of viruse with Anitibody of host cell can b done?

By: profvrr

profvrr — Tue, 01 Dec 2009 09:05:19 +0000

NEP used to be called NS2, nonstructural protein 2; encoded by a
second ORF in RNA 8. Then it was found in virions, interacting with
M1, and renamed NEP, nuclear export protein.

By: gsgs

gsgs — Tue, 01 Dec 2009 08:04:19 +0000

I didn't know NEP. Found it here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC114...
Nuclear Export Protein, NS2

54 comments 0 likes 2 points

By: Dipset on holidays

Dipset on holidays — Mon, 30 Nov 2009 20:23:20 +0000

i must disagree. this quite a poor portrayal of the virus. having worked on the frontline of various influenzas i have found that your RNA polyamearse is quite incorrect. kindly work on that sir.

By: devpriya11

devpriya11 — Sat, 21 Nov 2009 04:56:13 +0000

Brief explanatory and easy to understand

By: amy

amy — Sun, 15 Nov 2009 04:58:12 +0000

thank you so much for this explanation.It's very useful!

By: Aphrodite

Aphrodite — Sat, 07 Nov 2009 14:50:44 +0000

This helped me with my school project, thanks! BTW, I have the Swine Flu

By: Patriicia

Patriicia — Tue, 06 Oct 2009 07:00:10 +0000

Please, go on!

By: dd

dd — Mon, 28 Sep 2009 22:24:21 +0000

plez…explain more
i hve to presnt about it

By: mhtjsh

mhtjsh — Mon, 21 Sep 2009 09:43:24 +0000

hi, can you please explain in what respect does influenza virus a is differnt from type B and C. In short i am curious to knw abt the virus b and c as well .

By: rohinimylavarapu

rohinimylavarapu — Fri, 18 Sep 2009 01:54:20 +0000

the info given by you is very much useful…….may i know about the remedies for this virus.Also may i know about the remedies present in the food which we take to become immune to this virus…..?

By: Vanessa

Vanessa — Sun, 06 Sep 2009 07:31:35 +0000

I am a student and I am very interested in finding out such relavant and interesting stuff although it is not covered in our syllabus. Please continue. (: