TWiV #17: Seminal discoveries in virology

twiv_aa_2001On This Week in Virology episode #17, Vincent, Dick, and guest Saul Silverstein talk about discoveries in virology that have had a major impact on the field. By seminal, we mean “strongly influencing later developments”.

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  • Chris 26 January 2009, 5:19 pm

    I think you hit on most….
    A few others:
    PolyA on vaccinia mRNA (1970)
    Ribozyme activity associated with viral RNA (satellite tobacco ringspot virus) 1986

    vaccinia, largest genome sequenced (1990)
    Mimivirus (2004)

  • profvrr 26 January 2009, 7:18 pm

    Thanks Chris, good suggestions. Will add them in the next episode.

  • Everett 26 January 2009, 7:56 pm

    How about d'herelle and phage therapy? I just finished a good book about this called 'viruses vs. superbugs.'

  • Chris 27 January 2009, 1:19 am

    I think you hit on most….
    A few others:
    PolyA on vaccinia mRNA (1970)
    Ribozyme activity associated with viral RNA (satellite tobacco ringspot virus) 1986

    vaccinia, largest genome sequenced (1990)
    Mimivirus (2004)

  • profvrr 27 January 2009, 3:18 am

    Thanks Chris, good suggestions. Will add them in the next episode.

  • profvrr 27 January 2009, 3:55 am

    We mentioned D'Herelle for discovering bacteriophages….but using
    them as therapy never took off; they are too antigenic.

  • Everett 27 January 2009, 3:56 am

    How about d'herelle and phage therapy? I just finished a good book about this called 'viruses vs. superbugs.'